In response, Topps issued their "BIGGER is BETTER" 1952 Topps set they described as: "GIANT IN BOTH SIZE and NUMBER of CARDS" (407).

Series one cards (#1-80) can be found with black or red backs. The key card in the 1952 Topps set is card #311 MICKEY MANTLE. It is often called Mickey Mantle's Rookie card but it is not. The honor goes to his 1951 Bowman card. The 1952 Topps set also featured my favorite and THE greatest player of all-time, WILLIE MAYS !!! Again, this is sometimes called Willie Mays' Rookie card but it is not. That honor also goes to his 1951 Bowman card.

Another 1952 Topps card of note is card #1 Andy Pafko. Pafko, a fine player, is basically just a "Common card" and should be worth no more than any other "Common" in the 1952 Topps set - But SURPRIZE !!! It's worth TONS more because it's card #1 and absorbed much more damage than most cards from rubber bands and other damage, thus high grade cards are very, very tough to find accounting for the super high values.
BUT --- That should not account for the super high asking prices on lower grade copies. THose prices do not make sense (supply and demand).

The 6th (last) series, starts with #311 Mickey Mantle and ends with #407 Braves Hall-of-Famer Eddie Mathews. These "High Numbers" are significantly scarcer and can almost be called rare. In addition to Mickey Mantle, other star High Numbers included #312 Jackie Robinson and #314 Roy Campanella.

The most common explanation for their scarcity is as follows.
This HUGE set was released in series weeks apart. When it came to the last series the baseball season was winding down and football was starting. Most candy store owners had boxes of baseball cards leftover from earlier in the year so most eliminated their orders for the 6th series of 1952 Topps thus creating the scarcity.

To add interest to the story, it is often said that the unsold 6th series cards (including THOUSANDS of 1952 Topps MICKEY MANTLEs !!!) were disposed of by Topps, dumped offshore into the Atlantic Ocean like most of New York's trash in those days.